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There are two main incretin hormones in humans: GIP (glucose-dependent insulinotropic peptide
Standard IGF-1 IGF-1 LR3's reduced IGFBP binding makes it the preferred choice for in vitro research where consistent, predictable growth factor exposure is required
Some evidence suggests intermittent fasting increases GLP-1 sensitivity even without weight loss
It works by reducing appetite, controlling cravings, and improving blood-sugar regulation
Together, these mechanisms highlight the bidirectional interaction between gut and liver and support therapeutic strategies targeting microbiota composition and intestinal barrier integrity in MASLD
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