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The overall cost of semaglutide, including clinic visits and other associated expenses, can be substantial, necessitating open communication with healthcare providers regarding financial aspects before beginning treatment

This was the case in our pre-registered primary analysis (where we report a significant group effect across groups of participants with type-2 diabetes, on and off semaglutide, and BMI-matched and -unmatched healthy controls, which numerically show decreasing acceptance bias), and in our exploratory dimensional finding that increasing risk of diabetes is associated with lower acceptance bias across study groups

However, adverse GI effects, particularly nausea, constipation, and dyspepsia, remain notable considerations

They can offer guidance or adjust your dosage if needed

These benefits are due to the weight loss effects of GLP-1s, but the medication may also improve insulin sensitivity directly, too