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The observed LC-MS m/z will depend on the charge state, adducts, and data-processing conventions

This proliferation was further supported through immunohistochemistry images

This strategy has been exploited in the long-acting GLP-1RA semaglutide (Novo Nordisk), for instance, which was approved for treatment of T2DM in 2017, and for treatment of obesity in 2021, and has since then become the most prescribed GLP-1RA 92

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