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Intestinal extracts were then shown to potentiate insulin secretion in dogs and this led to the discovery of two primary gut hormones with incretin activity, gastric inhibitory peptide (GIP) and glucagon like peptide-1 (GLP-1) (10, 15, 18, 28, 75)

The solution is straightforward: split the dose into two injections administered at different sites within the same session

The FDA approved Rybelsus in 2019 and oral Wegovy in 2025 (Rybelsus was rebranded as oral Ozempic in 2026)

Michelsen, M.D., Ph.D., Jorge Plutzky, M.D., Christoffer W

After seeing how many chemicals are in the products women use every day, she wanted to create a healthier alternative for women