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Excessive neuronal iron promotes NFT formation via the activation of CDK5 (Cyclin-dependent kinase 5)/P25 complexes and GSK-3 (Glycogen synthase kinase-3 beta) kinase pathways
In 2025, Mounjaro led global GLP-1 drug sales, followed by Ozempic, Zepbound, and Wegovy
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And the emergence of GLP-1RA, such as semaglutide, exenatide, and efinopegdutide [116], and so on, can accelerate the drug development of NAFLD which has great therapeutic potential for the treatment of NAFLD [117]
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