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some studies extend to longer durations Dose amounts typically reported in mg per dose in clinical trial publications

Furthermore, another phase II trial, designed to assess the effect of CDDO-methyl ester on renal function in patients with DKD, revealed that CDDO-methyl ester significantly enhanced eGFR in patients with DKD

Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V

274,275 In addition, ginsenosides have been shown in laboratory and animal studies to reduce vascular inflammation and stiffness, stabilize atherosclerotic plaques, and slow atherosclerosis progression, which may help prevent thromboembolism

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