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Hansen et al., in their commentary on Humphrey and Lawrences paper [87], emphasized that several studies have demonstrated improvements in quality of life associated with GLP-1 RA-induced weight loss, along with health-related benefits such as enhanced cardiovascular outcomes that outweigh the impact of facial aging
Link: Anisimov VN, et al
PMID: 6145137
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With GLP-1 Agonists (e.g., Semaglutide, Tirzepatide): GLP-1s are powerful for fat loss but often cause nausea or gut discomfort
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