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Is 50 units considered a high dose of semaglutide The honest answer: it depends, but for most common concentrations, 50 units represents a moderate to high dose
However the incidence of acute pancreatitis with treatment is quite rare with 0.2 events per 100 person-years in the STEP1 trial
Mild-to-moderate gastrointestinal side effects were reported and were less prominent with titration up from a lower dose
Not what supplement marketing claims
Key safety concerns identified in Phase 2 data include elevated resting heart rate, gastrointestinal side effects, increased hypoglycaemia risk when combined with insulin or sulfonylureas, and class-relevant cautions around pancreatitis and thyroid C-cell tumours
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