Waldbillig RJ, Pfeffer BA, Schoen TJ, Adler AA, Shen-Orr Z, Scavo L, et al
Several viral infections, and the progression of virus-induced diseases, especially those associated with COVID-19, are characterized by an alteration in the intracellular redox balance (144, 145) and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease
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Evaluate whether you have reached an early plateau or simply a temporary stall
If patients experience intolerable side effects at a given dose, maintaining the current dose for an additional 4 weeks or temporarily reducing the dose may improve tolerance before attempting further escalation