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Interestingly, the mutation of ATP4Ap.R703C leads to gastric acid deficiency, and the disturbance of pH balance can directly affect the physiological function of the mitochondrial respiratory chain, causing ROS signaling to be activated and triggering caspase-3-mediated apoptosis in the host cells (Bentez et al., 2020)
Cunto tiempo tarda en notarse el glutatin
Microb Cell Fact 10(1):S17
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Oxidative Medicine and Cellular Longevity, 2013, 972913
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