Eur Surg Res
Combination therapy requires baseline kidney function assessment (eGFR) and periodic monitoring of renal markers, liver enzymes, and gastrointestinal symptoms
Wegovys active ingredient, semaglutide, works by mimicking the natural hormone GLP-1, which is crucial for regulating appetite, blood sugar levels, and insulin release
Adipose tissue dysfunction and altered systemic amino acid metabolism are associated with non-alcoholic fatty liver disease
Among 236 registered patients with T2DM, whose glycemic hemoglobin higher than 6.5% within 3 months, screened at our outpatient clinic, 102 subjects met the following criteria were enrolled: (1) age between 20 and 65 years, (2) diagnosis of type 2 diabetes for more than one year, (3) body mass index (BMI) 18 kg/m2 and 30 kg/m2, (4) fasting triglyceride 150 mg/dl or fasting low-density-lipoprotein cholesterol (LDL) 100 mg/dl and (5) willing to participate in and fill out questionnaires for this trial