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Other signal transduction systems and metabolic pathways involved in the MGB-based cause of depression include the endocannabinoid system, CAMKII-CREB and MAPK signaling, and glycerophospholipid metabolism
The targets are the GLP-1 receptor (glucagon-like peptide-1), the GIP receptor (glucose-dependent insulinotropic polypeptide), and the glucagon receptor
[1] [2] The Medicines and Healthcare products Regulatory Agency (MHRA) has approved its use to improve glycaemic control alongside diet and exercise
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