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Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors

MOTSc: Mitochondriaderived peptide with AMPK activation and insulin sensitivity effects

Therapeutic Research Protocol Dose: 1.2 2.4 mg (= 4896 clicks) Duration: 12 20 weeks Frequency: Once weekly Cycle Interval: 4 6 weeks off before repeating Goal / Description: Higher-dose protocol used in obesity research to evaluate sustained satiety and adiposity reduction

Berberine alleviates insulin resistance by reducing peripheral branched-chain amino acids

This IL-1 associated surge in Cx43 expression was diminished by exposure of the cell line to nobiletin (Kono et al., 2022)