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If the active compound can penetrate the skin's outer barrier (the stratum corneum) and reach the dermis and subcutaneous tissue, it enters systemic circulation through dermal capillaries without going through your GI tract or liver
How could the flagship product of a major health and beauty empire, once hailed as a pioneer, come to an end
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One large 2024 study in the journal Scientific Reports found that people with obesity who were taking GLP-1s had a slightly elevated risk of anxiety and suicidal behavior when compared to a control group, and almost double the risk of major depression
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