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Presentation of Graves orbitopathy within European Group On Graves Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)

Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature

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Practitioners prescribing semaglutide 0.15 mg, 0.25 mg per week - Microdoses -for conditions never studied, at doses never proven effective, based on a daisy chain of: Mouse studies that dont translate Dose-response curves that show threshold effects requiring higher doses Social media testimonials And wishful thinking From an insurance perspective, we cannot reimburse treatments without evidence of efficacy

Peptides with a long half-life (like Semaglutide or CJC-1295 w/ DAC) are administered weekly