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The demographic most commonly prescribed semaglutidemiddle-aged and older adults with obesity and metabolic conditionshas a high baseline prevalence of osteoarthritis, inflammatory arthritis, and other musculoskeletal disorders

Long-term follow-up for tumour incidence, organ function, regeneration outcomes

Patients with type 2 diabetes require alternative pharmacotherapy to maintain glycemic targets, while those using semaglutide for weight management benefit from structured lifestyle intervention programs to sustain weight loss

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