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442 Future progress will require coordinated breakthroughs in high-specificity clonal tracking, multiomicsbased mechanistic analysis, prospective clinical validation, and standardized workflow development for liquid biopsy to become a key tool in guiding strategies to overcome therapeutic resistance
However, more research is needed to determine which substances in asparagus are responsible for these positive effects, especially in humans
The VDR, which is widely expressed in hippocampal neurons and astrocytes, mediates the transcriptional regulation of antioxidant genes containing VD response elements (VDREs)
