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Prescribers have an obligation to explain that physician-prescribed, pharmacy-compounded HRT from an accredited pharmacy is fundamentally different from self-directed purchases of unregulated products

Moreover, cardiometabolic effects of GLP-1 are attenuated in obesity and T2D, via mechanisms that may involve impaired p38-MAPK signaling

Since growth hormone release is regulated by the hypothalamus and pituitary gland, any influence on these neural systems might indirectly affect GH secretion

Now anyone who is obese as defined by body mass index (BMI) or who is overweight per BMI and has at least one weight-related health condition is eligible for a GLP-1 prescription