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Figure 2 provides an integrated overview of ASTs effects on pathological processes relevant to neurodegenerative diseases, including oxidative stress, neuroinflammation, and synaptic dysfunction, which are particularly relevant in AD and PD pathology
150 mg/L AFB 1 (diluted in dimethyl sulfoxide), 2 mmol/L NADPH, 5 mmol/L GSH, rat cytosol, and recombinant GSTA2X (2.5 g total protein) were added at the same time
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This compounded medication has not been evaluated or approved by the FDA for safety or efficacy
Subsequently, lysates were centrifuged at 12,000 rpm for 15 min at 4 C to obtain clear supernatants
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