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A literature search was conducted covering studies published between 2016 and 2025 using platforms including PubMed, Web of Science (WoS), Scopus, and Google Scholar

Simultaneously, NAD+ levels increased by 1.2 to 1.6 fold compared to untreated cells

This increased HGH level enhances metabolic activity, supports muscle growth, and reduces body fat, contributing to weight loss and improved body composition

Vitamin Activation: Pantothenic Acid (Vitamin B5) supports coenzyme A, which is required for fatty acid metabolism

Sequential delivery of BMP-2 and IGF-1 using a chitosan gel with gelatin microspheres enhances early osteoblastic differentiation