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The 68-week trial, results of which were published last month in the New England Journal of Medicine, showed mean body weight dropping 13.7% and mean pain scores falling to 41.7 points from a mean of 70.9 on a 100-point scale
7.3Lanifibranor and other peroxisome proliferator-activated receptor (PPAR) agonists Lanifibranor, a pan-peroxisome proliferator-activated receptor (PPAR) agonist, exhibited significant improvements in MASH resolution and fibrosis in phase 2 trials [148]
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This was accomplished by screening a library of small molecule drugs that exhibited selective lethality in RAS-mutated cancer cell lines, thereby introducing a new non-apoptotic mechanism of cell death (24)
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This is because the data on the safety of taking the drug is limited
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