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Apart from apparently affecting the synthesis of growth hormone, scientists also suggest that CJC-1295 may interact with the survival and proliferation of the cells that synthesize it - the somatotroph cells in the anterior pituitary gland
The risk of it spreading is directly related to how deep the cancer has invaded the skin and whether the original cancer has broken down to form an ulcer
These trials will be critical in determining whether the promising phase 2 signals translate into robust, long-term clinical outcomes and an acceptable safety profile sufficient for regulatory submission to bodies such as the MHRA and EMA
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