Novo Nordisk has several GLP-1-based products for treating Type 2 diabetes: Ozempic (semaglutide, injection), Rybelsus (semaglutide, tablets), and Victoza (liraglutide)
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials
H., Dalkara, T., & Moskowitz, M
Nevertheless, many of the large-scale cardiovascular trials have reported the effects of DPP-4 inhibitors on aspects of diabetic nephropathy, specifically changes in urinary protein excretion, in glomerular function over time, and in the risk of progression to end-stage renal disease [47, 48, 84]
This article summarizes the key clinical trial findings, metabolic outcomes, body composition data, and safety profile that define retatrutides position in the research landscape