Hypoglycemia It is well known that GH, together with glucagon, cortisol, and epinephrine, display counterregulatory actions protecting from hypoglycemia, and that its excess may have a diabetogenic role as seen in subjects suffering from acromegaly ( In a double-blind RCT in T2D patients, a single dose of the GLP-1 analogue albiglutide did not impair the -cell response or GH secretion when blood glucose was clamped in the hypoglycemic range ( 2460 h), FFAs represent the key fuel of whole-body energy homeostasis
Chaumontet C, Azzout-Marniche D, Blais A, Chalvon-Dermersay T, Nadkarni NA, Piedcoq J, Fromentin G, Tom D, Even PC
Those are the only real concerns with an in-use Ozempic pen
& Pascual, V
[22] Dose adjustment strategies may be necessary for patients with persistent symptoms