Most of them are taken in a self-administered injectable format
The MHRA has issued warnings about unlicensed peptide products sold online due to concerns about quality, safety, contamination, and lack of regulatory oversight
There is no validated, MHRA-approved, or manufacturer-endorsed protocol for diluting or reconstituting retatrutide outside of an approved clinical trial
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Pipeline (Phase 3 trials completed, FDA decision pending as of April 2026): Survodutide (BI 456906): Dual GLP-1/glucagon agonist from Boehringer Ingelheim