semaglutide frequent urination Why GLP-1 medications may increase frequency How Does Semaglutide Work? Mechanism,

Hospitalizations due to major adverse cardiovascular events (such as strokes or heart attacks) dropped by 37% over two years after patients started GLP-1s

[1] In the SUSTAIN clinical trial programme , which evaluated semaglutide's efficacy and safety in thousands of patients with type 2 diabetes, anxiety was not reported as a statistically significant adverse event compared to placebo or active comparators

In a prospective study, high urinary betaine excretion was also associated with increased risk of heart failure in 325 subjects without diabetes mellitus who had been hospitalized for acute coronary syndrome (50)

Diabetes, Obesity, and Metabolism, 26 (S4), 16-27

AAV-mediated delivery of plakophilin-2a arrests progression of arrhythmogenic right ventricular cardiomyopathy in murine hearts: preclinical evidence supporting gene therapy in humans