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The 3.5 kb 5-flanking region of Iba1 gene was PCR-amplified from mouse genomic DNA and inserted into pBstN-NCre vector 67 to generate Iba1-Cre plasmid

For ABPP analyses only, outlier samples (based on low precursor identifications or clustering by principle coordinate analysis) were removed, leaving a minimum of 3/4 samples per condition

Although our disproportionality analysis did not identify headache as a statistically significant NAE signal, it represented the most frequently reported adverse event with 7,132 cases

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