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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available
This relative decrease in blood flow may predispose to thrombus formation in varicose veins and may be a significant contributing factor to the increased incidence of thrombophlebitis and deep vein thrombosis (DVT) in patients with varicose veins (see Chapter 2)
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Treating autism spectrum disorders There is some evidence that children with autism have lower levels of glutathione than neurotypical children, or those without autism
