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The peptide also inhibits 5-alpha reductase, the enzyme that converts testosterone to DHT, potentially reducing follicular miniaturization

Similarly, in fibroblasts from 26-month-old C57BL/6 mice, GHK reduced p21 and p53 expression (Figure 2B), further supporting its role in suppressing the senescent phenotype

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GHK Basic Studies on Insulin-Related Genes and Cellular Longevity Research indicates that GHK may modulate insulin and insulin-like gene expression, possibly impacting cellular lifespan

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