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More than 100 assets are currently in development, targeting novel mechanisms of action, combination therapies, and oral formulations [2]
They're checking for infection, inflammation markers, or organ function
The 500 Dalton rule (molecular weight below 500 Da correlates with percutaneous absorption) is a necessary but not sufficient condition, not a guarantee
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(2014) found eighteen metabolites in PBMC samples that discriminate between SCZ patients and HC subjects, while decreased levels of three metabolitespyroglutamic acid, sorbitol, and tocopherol contributed to the highest degree of separation between these two groups in all three cohorts
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