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Socinski MA, Kaye FJ, Spigel DR, Kudrik FJ, Ponce S, Ellis PM, et al

Antioxidant strategies based on tomato-enriched food or pyruvate do not affect disease onset and survival in an animal model of amyotrophic lateral sclerosis

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There is absolute chance of presence of undesirable particles or endotoxins in solution, so sterile filter is used in pharmaceutical industry to get rid of all of them