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If someone is telling you NAC is "proven to restore ovulation in PCOS" or "as effective as metformin," they are repackaging a small set of smaller studies and integrative-practitioner observations as something stronger than it is

Neural Regen Res 15(11):21432153 Zhang S, Rao S, Yang M, Ma C, Hong F, Yang S (2016) Protective effect of trans--viniferin against high glucose-induced oxidative stress in human umbilical vein endothelial cells through the SIRT1 pathway

Side effects are uncommon

But what if that wasnt necessary

If a compounded product contains peptide fragments, impurities, aggregates, degradation products, or an incompletely characterised active ingredient, the immune system may recognise parts of that product as foreign