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Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study
In India, obesity is defined at a lower Body Mass Index (BMI 25 kg/m) compared to global standards due to higher metabolic risks among Asian populations
Serious Side Effects (Rare But Important) Pancreatitis: Symptoms: Severe persistent abdominal pain, nausea/vomiting, fever Action: Stop medication, seek emergency care Gallbladder Disease: Increased risk with rapid weight loss Symptoms: Severe upper right pain, jaundice Action: Contact provider immediately Severe Allergic Reactions: Very rare Symptoms: Swelling, breathing difficulty, severe rash Action: Call 911 Kidney Problems: Usually secondary to dehydration Prevention: Maintain excellent hydration Thyroid Tumors: Based on animal studies FDA Black Box Warning Contraindicated with personal/family medullary thyroid carcinoma or MEN 2 Who Should NOT Use Absolute Contraindications: Personal/family medullary thyroid carcinoma history Multiple Endocrine Neoplasia syndrome type 2 Previous severe allergic reaction Pregnancy or planning pregnancy Breastfeeding Relative Contraindications (Careful Evaluation Required): Pancreatitis history Severe gastroparesis Inflammatory bowel disease Severe eating disorders Severe kidney disease Active gallbladder disease Diabetic retinopathy Making Your Decision The following framework is informational and does not replace individualized medical advice from a licensed clinician
Cancer (2020) 126(20):222549
Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A
