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In PNA mice, that display modest metabolic dysregulation and overt gonadal perturbations, all multi-agonists decreased body weight (Fig
Similar patterns of severe mitochondrial impairment have been extensively documented in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Together with Derek Holdsworth, another gastroenterologist trainee, and Desmond Turner, a biochemist, McIntyre decided to revisit La Barre's hypothesis that the duodenum encouraged the pancreas to produce insulin by releasing incretin
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