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[8] [9] [10] A substudy in adults with type 2 diabetes reported differences in total body fat mass between study groups at 36 weeks
The key concern lies in the potential for additive blood glucose-lowering effects
conducted a magnetic resonance imaging (MRI) study and found that long-term chronic hyperglycemia can mediate hippocampal dysfunction, 19 and hyperglycemia inflammatory mediators, rheological factors, and dysregulation of the hypothalamicpituitaryadrenal axis also may exacerbate cognitive decline
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