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A 2025 University of Virginia study concluded that while GLP-1 drugs significantly reduce body weight and adiposity, they do so "with no clear evidence of cardiorespiratory fitness enhancement"a critical finding given that cardiorespiratory fitness is among the most potent predictors of all-cause and cardiovascular mortality [48]
However, a 2024 study published in Obesity recommends an evidence-based approach centered on a healthy dietary pattern that includes vegetables, fruits, whole grains, lean proteins, low-fat dairy, and healthy fats
At the highest dose of retatrutide, more than 90% of participants with obesity and NAFLD achieved normalization of liver fat
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Reduces Visceral Fat Tesamorelin promotes the release of growth hormone from the pituitary gland, leading to increased lipolysis especially in the abdominal region
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