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El mecanismo para este efecto metablico de la carnitina no ha sido completamente clarificado, pero se han propuesto varias acciones de carnitina relacionadas con dicho efecto: Regulacin del transporte de acetilo y acilo entre los compartimentos intracelulares Regulacin de la actividad del complejo piruvato deshidrogenasa Modulacin de la expresin de genes que codifican enzimas glucolticas y gluconeognicas y componentes de la cascada de sealizacin de la insulina Estimulacin del factor de crecimiento insulnico (IGF)
menstruating women, especially those with heavy periods
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2.5 Anti-angiogenic effect Abnormal angiogenesis plays a significant role in the pathogenesis of several eye diseases, particularly those involving retinal ischemia and neovascularization
Prediabetes alone is not a qualifying severe comorbidity under Kaiser PA criteria
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