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Begin with alternate-day application and progress to daily use after two weeks without irritation
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Side Effects & Safety Per REDEFINE 1 and the Lau (2021) phase 2 program, trial-reported adverse events include: Nausea -- most common (25-40%)
Because the Kras G12D -Myc axis has been suggested to induce Nrf2 gene expression and increased the activity of Nrf2 in pancreatic cancers ( Another unique regulator of the pentose phosphate pathway is the tumor suppressor p53, which inhibits the pentose phosphate pathway through binding to G6PD and preventing the formation of the active dimer (Jiang et al., 2011)
Thats a reasonable shorthand, but it undersells how far this is from a finished process
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