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The pharmaceutical formulation disclosed herein may comprise 10-25% w/v, such as more than 10% w/v and less than 22% w/v, such as about 10-20% w/v, such as about 12- 18% w/v, such as about 10-17.5% w/v, such as about 11.25-15%, such as about 15% w/v hydroxypropyl-beta-cyclodextrin having a minimum of about 0.4 hydroxypropyls per glucose unit and a maximum of about 1.0 hydroxypropyls per glucose unit
Clinical studies indicate 1-3% concentrations deliver optimal efficacy for skin remodeling benefits without irritation
43 CojocaruK.-A.LuchianI.GoriucA.AntociL.-M.CiobanuC.-G.PopescuR.et al (2023)
Rossignol DA, Frye RE
Use within validated timeframes: Reconstituted peptide solutions stored at 2-8C should generally be used within 4-6 weeks maximum, with many vendors recommending 7-14 days
