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These signals enhance mitochondrial fitness, restore redox homeostasis, attenuate pro-inflammatory glycolysis, and stabilize endothelial-pericyte coupling to stabilize a permissive neurorehabilitation microenvironment

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The results from Micro-CT 3D reconstructions and quantitative analysis showed that implanted scaffolds containing testosterone increased TV, new bone formation and completed callus bridging across the fracture gap in AR flox/Y mice, but not in AR -/Y ;Prrx1::Cre mice (Fig

[PubMed: 17068142] Alba M, et al