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According to American Thyroid Association guidelines, treatment is typically initiated when TSH rises above 10 mIU/L or when TSH is between 4.5-10 mIU/L with symptoms or positive thyroid antibodies
Adherence in routine practice is likely lower, and reduced adherence directly affects absorption and efficacy
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doi: 10.1096/fj.14-265983 20 QinJLiYCaiZLiSZhuJZhangFet al
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