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Linda Assatourians is a clinical reviewer in the Division of Clinical Review within the Office of Safety and Clinical Evaluation, where she began her career at the FDA in 2023

Moreover, in contrast to rat kidney mitochondria, the import of GSH in rat liver mitochondria showed both a high affinity and low affinity transport component (Martensson et al., 1990)

Weight loss compounds present a fundamental problem: they typically require much larger doses to be effective than can realistically be delivered through the skin

Comparing GLP-1s for Medical Weight Loss Updated:January 2, 2026 Learn the Key Differences Between Todays Top GLP-1 Medications for Safe, Sustainable Medical Weight Loss in Atlanta, GA

Potential medical causes of excessive fatigue: Thyroid dysfunction: Wegovy may rarely affect thyroid function Anaemia: Reduced food intake may lead to iron or B12 deficiency Dehydration: Particularly if experiencing diarrhoea or vomiting Hypoglycaemia: Low blood sugar, more common if taking diabetes medications Medication interactions: Wegovy may interact with other medications Key points: Normal Wegovy fatigue gradually improves and doesnt severely impact daily functioning Consult your healthcare provider if fatigue is severe, worsening, or accompanied by other concerning symptoms Simple blood tests can identify underlying medical causes of excessive fatigue Dose adjustments may be necessary if fatigue significantly impacts quality of life Frequently asked questions about Wegovy and tiredness How long does Wegovy fatigue last