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Considering the low oral GABA dose administered, it was not unforeseen that only glucagon inhibition was detected, corroborating the paracrine inhibitory effect of -cell GABA on -cells

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PMID 27726382

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Firstly, the 1-g and 4-g PV1 sVLP doses tested in the study contain 187 and 748 DU, respectively, which are much higher than a single human dose (40 DU) of commercial IPV, making it difficult to directly compare the immunogenicity of sVLP and IPV

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