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Limitations of current therapeutic strategies Current clinical management of RIRI primarily relies on antioxidant agentssuch as N-acetylcysteine and vitamins E/Canti-inflammatory drugs including non-steroidal anti-inflammatory agents (NSAIDs), and nephroprotective compounds like amino acids and indomethacin, often supplemented by supportive measures such as fluid resuscitation and extracorporeal blood purification

Adhikari D, Lee I, Yuen WS, Carroll J

Keep the fire burning: current avenues in the quest of treating mitochondrial disorders

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Self-medicating or using medications off-licence without medical supervision can be dangerous and is not supported by current evidence