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Role of renal sympathetic nerves in GLP-1 (glucagon-like peptide-1) receptor agonist exendin-4-mediated diuresis and natriuresis in diet-induced obese rats
In type 2 diabetes, collagen improves glucose homeostasis by enhancing insulin sensitivity, upregulating GLUT-4 and inhibiting dipeptidyl peptidase IV (DPP-IV), thereby prolonging incretin activity (GLP-1 and GIP) and supporting -cell function
doi: 10.3389/fphar.2023.1182788 Received 09 March 2023 Accepted 31 March 2023 Published 06 April 2023 Volume 14 - 2023 Edited by Xuelin Zhou, Capital Medical University, China Reviewed by Yachen Shen, University of Pennsylvania, United States Yusheng Li, University of Mississippi, United States Shengjie Xu, Merck, United States Changlu Xu, University of California, Los Angeles, United States Updates Copyright 2023 Jing, Iba, Naito, Xu, Morishige, Nagata, Okubo and Ando