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854 Changes associated with ferroptosis in the cartilage of the injured articular area in OA patients, including GPX4 downregulation, ACSL4 upregulation, MDA accumulation, and mitochondrial morphological and function changes, are more severe than in the intact articular area and worsen with OA progression

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We just end up talking about, you can take it in the short-term, but we dont know anything about whats going to happen if you take them in the short-term or the long-term, said Mehrotra

Presented for research literature review only Gabery S et al