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There are five types of melanocortin receptors, MC1R, MC@R, MC3R, MC4R and MC5R

It works by: inhibiting the enzyme tyrosinase reducing melanin formation in treated areas helping lighten hyperpigmented spots It does not affect: internal antioxidant balance liver detox pathways overall systemic melanin regulation It is a targeted external solution, not an internal support system

low approval of Studies and limited research create large uncertainty Trutan Education and safety are priorities through responsible perspective

Drafting of the manuscript: Kumar and All authors

Pricing figures are up to date as of January 2026