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Together, they create an environment optimized for both repair and enhancement

The sequence of the BH3 peptides has been previously reported 93,94

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Evolution of procaspase-1-cleaving proteases Our initial campaign targeted cleavage within the interdomain linker (IDL) of procaspase-1

for instance, DT-109 (Gly-Gly-Leu) markedly reduced atherosclerosis and vascular calcification in nonhuman primates, underscoring the translational potential of tripeptide-based therapeutics for cardiovascular diseases [181]