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Several potential interactions deserve attention in the hepatic impairment population specifically
Beekman B, et al
Rapid weight loss from any mechanism can trigger telogen effluvium, a temporary form of hair shedding
These include phentermine and topiramate
1) are dysregulated in response to the GDH2 gene deletion, or these pathways are unable to generate sufficient glutamate inside the cells and the large pool of free NADP + required to overcome the thermodynamic barrier inherent in using the still present Gdh3, which is usually an anabolic enzyme with a higher affinity for -ketoglutarate than for glutamate
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