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HS patients with obesity or Type 2 diabetes experienced the most benefits

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GLP-1 receptor agonists demonstrate modest but clinically relevant effects on lipid profiles , though they are not primarily indicated for cholesterol management

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The STEP 1 clinical trial demonstrated average weight loss of approximately 15% of body weight over 68 weeks with semaglutide 2.4mg, but these results were achieved in conjunction with dietary counselling and a 500 kcal per day calorie deficit, as highlighted in NICE TA875